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Phase 3 trial protocols allow dose reduction at lower BMI levels rather than stopping treatment

[DOI] [PubMed] [Google Scholar] 200.Hao Y, Zhu YJ, Zou S, Zhou P, Hu YW, Zhao QX, et al

If your test results suggest higher individual sensitivity to GLP-1 effects, you can agree in advance on clearer pause-versus-continue criteria for future acute illness, reducing uncertainty and supporting faster, evidence-informed decisions when you're most vulnerable

This process enhances oxidative phosphorylation, promotes metabolic flexibility, and supports MM drug resistance

If you notice unexpectedly elevated blood glucose readings or diminished therapeutic effects, discuss these changes with your healthcare provider

I continue on my HRT journey as well and plan to take it forever