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Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants

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[DOI] [PMC free article] [PubMed] [Google Scholar] 172.Deng X., Xiong X., Khomenko T., Sandor Z., Osapay K., Tolstanova G., Shiloach J., Chen L., Folkman J., Szabo S

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These alterations, in turn, can engage host BA receptors like Farnesoid X Receptor (FXR) and Takeda G protein-coupled Receptor 5 (TGR5/GPBAR1) on immune and cancer cells, thereby influencing anti-tumor immune responses and the efficacy of treatments such as immune checkpoint inhibitors (ICIs)

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