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In phase I metabolism, GSTs catalyse the nucleophilic attack of the thiol group of reduced glutathione located in the electrophilic centre of lipophilic compounds, including OPs and pyrethroids, causing increased water solubility and excretion by the cells [118, 122, 123]

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Anxiety and depression associated with increased cardiovascular disease risk through accelerated development of risk factors

doi: 10.1073/pnas.1001006107 41 LiuJZhangCWangJHuWFengZ

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These findings underscore the significant impact of vitreous opacities on visual function and quality of life, highlighting the need for greater recognition of this condition as a legitimate medical concern requiring appropriate management and treatment options