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Firstly the Review was based on research papers that were very suspect and involved groups of individuals that did not represent a wide cross section of society (the primary study was of mainly elderly males)

And the metabolic endpoint being measured

Peptide Weight Loss in Stamford and Connecticut Across Fairfield County and the broader Connecticut region, more medical practices and wellness centers are promoting peptidebased weightloss programs, often alongside GLP1 plans like semaglutide or tirzepatide

Andres E, Dali-Youcef N, Serraj K et al

Below are some of the reasons for taking vitamin B12 treatments

it does not endorse human use