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Description
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Clinical features include signs of dehydration, tachycardia, postural hypotension, mood changes, insomnia, decreased concentration and feelings of anxiety and depression

10.1136/bmj.l4898
Further comprehensive studies elucidating detailed roles of HIF-1 in certain stages of OA pathogenic progression, as well as detailed mechanisms on hypoxia-induced LOXs expression and activity, require further elucidation
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