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Studies show an average weight loss of 15-20% of body weight over 68 weeks with drugs like semaglutide or tirzepatide, though results depend on individual factors and adherence

Wegovy FDAapproved since FDAapproved since June 2021 for chronic weight management in adults with obesity or overweight and at least one weight-related condition (e.g., hypertension, type 2 diabetes, or high cholesterol)

But, if youre currently on semaglutide or considering semaglutide to support your weight loss journey, feel reassured that its unlikely to adversely affect your muscle and lean tissues if you approach weight loss in the right way

Beyond their well-established benefits for blood sugar regulation and weight control, GLP-1RAs also exhibit various biological activities associated with both insulinotropic effects and immunoregulation

Novo Nordisk launched the product in the United States in January 2026, marking the first time an oral GLP-1 treatment had been cleared specifically for weight management

People using GLP-1 medication at their standard dose may experience the full therapeutic effect, in contrast to others who are microdosing