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At the end of the study, a reduction in the visibility of dark circles was observed in all volunteers

Yu Shi An Chang Fang, a typical Chinese medicine prescription, may effectively manage oxidative stress by increasing the activities of antioxidant enzymes such as SOD, catalase (CAT), and glutathione peroxidase (GPX), while reducing tissue malondialdehyde (MDA) levels [96]

Under oxidative stress, Keap1 is modified and releases Nrf2 to enter the nucleus and promote gene transcription

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[DOI] [PubMed] [Google Scholar] Tao X., Gou J., Zhang Q., Tan X., Ren T., Yao Q., Tian B., Kou L., Zhang L., Tang X