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Description
Patients were randomly assigned to receive albumin or saline weekly
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In 1973, Russell Doolittle (19312019) indicated that a large disordered region of fibrinogen enabled its cleavage and activation, indicating functional importance of IDR (Doolittle, 1973)

Cell (2020) 182(2):27096

The solution was buffer exchanged through tangential flow filtration to remove residual organics to eliminate interference for downstream purification
Kawai, J
