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In the treatment with three active ingredients the subjects were administered for 16 weeks daily dosing of 5 grams of hydrolyzed collagen (HC) with 80 mg of vitamin C and 30 mg of hyaluronic acid (triple treatment n = 28)

exposed HepG2 cells to 520 M TSN for up to 24 h and showed a 15% loss of cell viability that correlated with partial GSH depletion, a three-fold increase in LPO, and reduced GPx4 expression

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SSADH provide succinate into TCA cycle by conversion of succinate semialdehyde (SSA) into succinate (Shelp et al., 2021)

Exercise induces autophagy

Trimetazidine ameliorates myocardial metabolic remodeling in isoproterenol-induced rats through regulating ketone body metabolism via activating AMPK and PPAR alpha