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doi: 10.1016/j.jim.2019.07.001 Summary Keywords Friedreichs Ataxia, bloodbrain barrier, tight junction, Claudin-5, Occludin, ZO-1, transendothelial electrical resistance, mitochondrial energy metabolism Citation Smith FM and Kosman DJ (2025) Brain microvascular endothelial cells differentiated from a Friedreichs Ataxia patient iPSC are deficient in tight junction protein expression and paracellularly permeable

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190 The observation that oncogenic KRAS promotes MYC protein stability 191 further complicates this scenario

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