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Mucolytic (mucus-thinning) action One of NAC's well-established properties is its ability to thin mucus secretions

This induction is significantly attenuated in Nrf2-deficient keratinocytes, indicating that 4-HNEs effects are mediated, at least in part, through the Nrf2 pathway [45]

In their research, they applied the Pavia Protocol consisting of 150 mg/kg intravenous NAC followed by 300 mg/kg/day until 48 h after poisoning, alongside forced diuresis until negative urinary amanitin levels were obtained

Primary hyperalgesia after tissue injury is suggested to result from sensitization of primary afferent fibers, but sensitization to mechanical stimuli has been difficult to demonstrate