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This section examines the combined efficacy of AS-IV with other TCM components, as well as its ability to reduce side effects when used in conjunction with cardiovascular drugs such as metoprolol and aspirin

9 Further, factors such as exposures to phthalates, atmospheric mercury levels, and total blood mercury have remained relatively stable since the 1990s, although exposure to polybrominated diphenyl ethers (PBDEs) and glyphosates has increased
PMID: 34714971

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As research progresses from molecular subtyping and metabolic mechanisms to therapeutic combinations and clinical validation, mitochondrial metabolic reprogramming has evolved from a fundamental biological question into a cornerstone of precision intervention
