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KEAP1 acts as an OS sensor to regulate NRF2 turnover within the cell/body, while NRF2 activation leads to the production of antioxidant and detoxifying substances that decrease OS [66,67,68]

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Abiotic stresses generally result in overproduction of reactive oxygen species (ROS) such as singlet oxygen ( 1 O 2 ), superoxide (O 2 ), hydrogen peroxide (H 2 O 2 ) and hydroxyl radical (OH)

Isoliquiritin apioside relieves intestinal ischemia/reperfusion-induced acute lung injury by blocking Hif-1-mediated ferroptosis

How Melanin Determines Skin Tone Skin colour is primarily determined by melanin, a pigment produced by specialised cells called melanocytes in the basal layer of the epidermis