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Related studies have also shown that upregulating GPX4 expression can alleviate brain damage in VD rats, while knocking out the GPX4 gene exacerbates brain damage (Ming et al., 2023)

The combined-formulation Phase 3 REDEFINE-1 data (PMID 40544433) extended the tolerability characterisation into the larger and longer-duration cohort

Wight, J., Chilcott, J., Holmes, M

These interactions were observed at high resolution for a loop within the TDMD sensor domain that we term RNA-binding element 1 (RBE1

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& Aoki, F