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CrossRef Pre-existing minor variants with NS5A L31M/V-Y93H double substitution are closely linked to virologic failure with asunaprevir plus daclatasvir treatment for genotype 1b hepatitis C virus infection Naoki Morishita, Ryotaro Sakamori, Tomomi Yamada, Yugo Kai, Yuki Tahata, Ayako Urabe, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Yoshinori Doi, Shinji Tamura, Hideki Hagiwara, Yasuharu Imai, Sadaharu Iio, Tomohide Tatsumi, Tetsuo Takehara, Jason Blacka PLOS ONE .2020

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28 The association between sleep apnea and blood pressure is likely bidirectional and driven by a number of factors, including overactivation of the sympathetic nervous system, oxidative stress resulting from intermittent hypoxia (periods of low oxygen levels), and disruption of hormone levels

It also supports detoxification mechanisms which contribute to liver health which in turn bolsters nutrient use throughout the body

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