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Vitamin B12 deficiency can also cause a condition called jaundice, which makes your skin and the whites of your eyes take on a yellowish color

You move from a pre-filled pen to a vial and syringe

This is particularly true for those who were severely B12 deficient

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The illness is characterized by gradual loss of dopaminergic neurons in the substantia nigra and the appearance of Lewy bodies, which include aggregation of alpha-synuclein, extensively dispersed proteins in the cerebral tissues

To sum up, some patients report the worsening of symptoms within the first few days or weeks when they begin B12 shots