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In the parotid gland mitochondria, despite an undoubtedly significant improvement of these parameters compared to the HFD group (59% GSH, 19% GSSG, 186% GSH/GSSG ratio), we still observed considerably reduced GSH concentration (21%), increased GSSG (31%) and decreased GSH/GSSG ratio (50%) compared to the control group

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More so, ZG suppresses the activities of enzymes like cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), thus inhibiting the production of inflammatory mediators, e.g

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