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Ferroptosis involves multiple pathways including redox balance, iron regulation, mitochondrial function, and amino acid, lipid, and glycometabolism

It is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice

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A recent study that examined the neuroprotective effects of CGA in hypoxia-ischemia brain injury in neonatal rats showed that the compound activates Sirtuin1 to regulate the NRF2/nuclear factor kappa B (NF-B) signaling pathway and protects primary neurons from damage induced by oxygen and glucose deprivation [78]

doi: 10.1016/j.chembiol.2020.03.013 187 LuoYGaoXZouLLeiMFengJHuZ

Multiple studies have demonstrated that consistent administration of HCQ and CQ during the first five years of the disease improves treatment outcomes, whether used as monotherapy or in combination with other therapies (104)