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Description
Effector Treg cells take up lactate through MCT1 to enhance PD-1 expression and remodel its function and phenotype, which may be one of the reasons for resistance to PD-1 immunotherapy [16]

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Elusive goal of targeting tumor hypoxia fortherapeutic gain
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RFNL: retinal nerve fibre layer thickness

One study found that 24% of chronic fatigue patients had DNA from the Epstein-Barr virus in their plasma, in comparison with only 4% of the control group.[ref] Herpes simplex, CMV : Other studies point to a variety of other possible viral triggers for ME/CFS, including herpes simplex or cytomegalovirus, but not all studies agree.[ref] HHV-6: Researchers examined brain and spinal cord postmortem tissue samples from ME/CFS patients
