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As mentioned in this review, while the loss of SNpc dopaminergic neurons causes the primary motor symptoms of PD, the pathology is not solely restricted to these neurons

H., Kim J

doi: 10.1097/MPG.0000000000002708 289

(2024) 6:fcad353

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In macrophages, LPS binds to TLR4 in the presence of LPS-binding protein (LBP), CD14, and MD-2 (present on the extracellular domain of TLR4) (156)
