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The intense inflammation and damage to skin tissue often result in scarring, which can significantly impact cosmetic appearance and overall skin quality

Biological activities of fibroblast growth factors

Besides, nutraceuticals, including acety-L-carnitine, glutamine, vitamin E and A-Lipoic acid, have also been applied for CIPN intervention but achieved little positive clinical outcomes (Table 2 ) [126]

doi: 10.1038/sj.mt.6300394

The proliferation and production of granzyme B are not dependent on Glut1 [98] (Fig

Early warning signs include persistent fatigue that does not improve with rest, difficulty concentrating or brain fog, tingling or numbness in hands and feet, weakness in the legs, dizziness when standing up, pale or yellowish skin, and a sore or swollen tongue