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each conformation preferentially interacts with selective partners producing specific signaling cascades (Kenakin, i/o proteins (Allouche et al., in vivo effects (see below) (Raehal et al., In vivo function The anatomical localization of OR in the brain and peripheral tissues has been clearly established using autoradiographic methods with selective radiolabeled ligands and detection of OR transcripts using in situ hybridization (Mansour et al., The highest density of MOR is found in the caudate and putamen, where they exhibit a typical patchy distribution in the rat

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Eastern European regions undergoing post-transition economic restructuring often lack capital investment and monitoring capacity, resulting in slower adoption of advanced recovery technologies 152,153

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In Fields Virology (ed