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Moreover, sustained elevation of CORT can induce the upregulation of pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNF-), enhance microglial activation, disrupt bloodbrain barrier (BBB) integrity, and facilitate the infiltration of peripheral immune cells into the central nervous system (CNS), thereby exacerbating neuroinflammation (Hooper et al., 2018)

A small subcutaneous injection, usually taken before bedtime to match natural GH release cycles

doi: 10.1016/j.cmet.2010.11.008

10.3390/molecules16086732 38 JiangH.WangX.HuangL.LuoZ.SuT.DingK.et al (2011)

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This can lead to an incorrect diagnosis or improper dosing of your medication