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At the juxtaparanodes, contactin-2 interacts with Caspr2, and this association is necessary for clustering of voltage-gated potassium channels

Many of these are injectable medicines that work on hormonal pathways controlling hunger

Funding This work is supported by the National Natural Science Foundation of China (82073477 and 82003390), the Technology Innovation Project of Chengdu (2021-YF05-01603-SN) and the Young Talent Program of China National Nuclear Corporation

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Its extended half-life of approximately 36 hours compared to endogenous LH makes it a practical tool for sustained receptor stimulation in experimental protocols