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Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart

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10.1055/s-0031-1298431 73 EdlerM

log-transformed LFQ intensities

Epigenetic effects include modulation of chromatin structure and DNA methylation, promoting access to beneficial genes while repressing harmful ones

In general, it is better to perform a study to determine the MTD in the population of patients for whom the therapy will be intended, because sometimes patients have a different susceptibility to an event compared with healthy people.55 On the other hand, sometimes patients will more often have certain symptoms or findings that are part of their disease, making interpretation difficult