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As a result, the MICG advises that women diagnosed with LS maintain a healthy diet, avoid obesity, engage in regular exercise, avoid smoking and avoid known carcinogens as part of their prevention program (22)

doi: 10.3390/ijms23116263, 92

Fox summarizes key takeaways

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To counteract ERS, cells initiate the UPR via three major pathwaysPERK, inositol-requiring enzyme 1 (IRE1), and activating transcription factor 6 (ATF6)to coordinate adaptive repair and death decisions [206]