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The animals treated with melatonin for 18 months showed high levels of APE1 (Apurinic/apyrimidinic endonuclease 1) and OGG1 (8-Oxoguanine glycosylase), two important enzymes involved in the base excision repair pathways of DNA lesions

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Furthermore, combining WFA with Fer-1 reduces hemin-induced neuronal damage in SH-SY5Y cells, reinforcing the therapeutic potential of dual ferroptosis inhibition (196)

MCT oil may specifically attenuate the ethanol-induced upregulation of CYP2E1 and production of mitochondrial 4-hydroxynonenal, a marker of oxidative stress [64]

476,477 Genetic code reprogramming by substituting endogenous aaRSs for more promiscuous mutants, such as PheRS A294G, LeuRS D345A, and editing deficient ValRS T222P, has also been reported