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Here this group reports a ruthenium-based nanocatalyst alleviating hypoxic TME, activating protein transient receptor potential melastatin 2 ion channel, promoting systemic immune response thereby eliciting its therapeutic efficacy against osteosarcoma.

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Here, we present self-assembled querce-tin-Fe3+ nanoparticles (Qu-Fe NPs) for synergetic near-infrared (NIR) light-triggered low-temperature PTT (LTPTT) and glutathione (GSH)-activated CDT