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In addition, oxidative stress contributes to insulin resistance in the periphery by disturbing glucose transport 4 (GLUT4), resulting in the maintenance of elevated blood glucose levels [123]

Its mechanism may involve an increase in endogenous glutathione, attenuation of oxidative stress, and enhanced synaptic plasticity [35, 53, 54]

Endothelial nitric oxide synthase (eNOS) and the cardiovascular system: in physiology and in disease states
Forster R, Spzia F, Papineau D, et al

Statements Author contributions All authors contributed to this perspective article

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