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However, substantial interindividual pharmacokinetic (PK) and pharmacodynamic (PD) variability have been observed among older patients taking the reduced S-CIT dose of 10 mg QD

Majewski, M

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More serious but less common adverse effects observed in trials or associated with this drug class include: Increased heart rate , a class effect seen with GLP-1 receptor agonists [15] [12] Gallbladder disease , including gallstones (cholelithiasis), which has been associated with rapid weight loss and incretin-based therapies more broadly

Fabry disease: baseline medical characteristics of a cohort of 1765 males and females in the Fabry Registry