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The aetiology of pain is a complex, transdisciplinary process with multiple causes, including cancer, rheumatoid arthritis, spinal problems, injuries and surgery (2)
Among the various compounds tested, PROTACs 62 (DC 50 = 0.11 M, D max = 87%) and 63 (DC 50 = 0.16 M, D max = 85%) stand out with the most robust in vitro cytotoxic effect against FaDu and resistant KM3/BTZ cell lines
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Craft S, Claxton A, Baker LD, Hanson AJ, Cholerton B, Trittschuh EH, et al
Nemeth C, Humpeler S, Kallay E, Mesteri I, Svoboda M, Rgelsperger O, Ekmekcioglu C (2011) Decreased expression of the melatonin receptor 1 in human colorectal adenocarcinomas
Mason SA, Keske MA, Wadley GD
