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GPX4 [including cytosol- and mitochondria-localized GPX4 (GPX4 cyto and GPX4 mito )] is the first reported anti-ferroptosis pathway [55]

It was reported that overexpression of WT DJ-1 enhances cell resistance to DA toxicity and inhibits ROS generation [136]

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In addition, glutathione reductase (GR) in the presence of NADPH restores reduced glutathione (GSH) from its oxidized GSSG form

In the 22Rv1 cell model, Nano-PROTAC degraded 80% of the AR protein and 65% of the HSP90 protein

[DOI] [PubMed] [Google Scholar] 36.McAnulty SR, McAnulty LS, Nieman DC