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Notably, there is an increased prevalence of Bacteroidetes, which are implicated in the fermentation of polysaccharides, as well as specific bacterial groups such as Prevotella , Ruminococcus , and Roseburia , which produce SCFAs (113)

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This modulation may influence the expression of key inflammatory mediators such as tumor necrosis factor- (TNF-), thereby improving the wound microenvironment in diabetes (134)