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It is characterised by its selective interaction with NNMT (Nicotinamide-N-Methyltransferase) , an enzyme implicated in a range of metabolic and biochemical regulatory processes, making it a valuable reference compound for preclinical and in-vitro research programmes

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2009;297(3 ): E70816

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Inborn errors in cobalamin metabolism, such as cblC defects, can result in a range of neurological manifestations, including demyelination and neurotoxicity [98] and have even been linked to MS [99]