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Although the complete molecular mechanism underlying changes in GCL expression during chronic cholestasis or in response to UDCA has not yet been clarified, Yang and colleagues showed a transient and early increase in GSH-related enzymes, followed by their dramatic decrease in a second phase of cholestasis

MC exposure to pregnant rats may lead to fetal exposure to MC as well as CO [11]

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Fumarate induces redox-dependent senescence by modifying glutathione metabolism

Am J Occup Ther