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The most direct way to study a proposed lipolytic agent is in isolated fat cells or adipose explants, measuring glycerol and free-fatty-acid release into the medium, cAMP accumulation, and the phosphorylation state of HSL

2b and c, ICA-1s showed a significant cytotoxicity ( P 0.01) on both metastatic prostate cancer cell lines (DU-145 and PC-3)

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