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In conclusion, NETs induced by MSU crystals exhibit dual pathological functions in gouty arthritis
HurstRArmahCNDaintyJRHartDJTeucherBGoldsonAJet al
Zhao X, Jin L, Liu Y, Liu Z, Liu Q
doi: 10.1038/s41398-019-0378-9
The metabolic rate and RQ were measured from 7 pm to 1 pm (19:007:00, dark phase
Activated XBP1 drives an abnormal triglyceride biosynthesis program, causing further lipid accumulation within tDCs, ultimately hindering their antigen-presenting ability and preventing them from effectively activating tumor-infiltrating T cells, thereby suppressing the anti-tumor immune response [159]
