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PubMed link This study showed a significant increase in AMPAR GluR1-mediated glutamatergic neurotransmission in excitatory synapses on hippocampal CA1 neurons during benzodiazepine withdrawal, which gives insight into the physiological mechanisms underlying benzodiazepine-induced withdrawal anxiety

Remethylation of homocysteine via MS requires 5-methyltetrahydrofolate (5-MTHF), which is derived from 5,10-methylenetetrahydrofolate (5,10-MTHF) in a reaction catalyzed by methylenetetrahydrofolate reductase (MTHFR)