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In post-viral syndromes, chronic neuroinflammation often causes excess glutamate to accumulate in the synaptic cleft, where it becomes highly neurotoxic and overstimulates neurons to the point of cell death

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Clearance of the necrotic site and regeneration through proliferation of healthy cells are necessary for complete recovery after injury, yet such recovery is likely hampered by senescent cells that can no longer proliferate

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