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The composition and activity of immature brain NMDA receptors differ from those identified in the adult brain, and their sensitivity to HI conditions increases excitotoxic damage (2)

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( i ) V/[E] (min 1 ) values from (d-f) were extrapolated (mean SEM)

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The normal process of aging is associated with a decrease in glutathione activity, which can result in increased oxidative activity

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By inducing autophagy, resveratrol promotes the degradation of damaged cellular components, leading to cell death and inhibition of tumor growth

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N Engl J Med 367: 817825, 2012

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Remaining challenges include particle aggregation and potential toxicity, which have limited the number of polymer-based nanomedicines approved for clinical use [21]

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