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The composition and activity of immature brain NMDA receptors differ from those identified in the adult brain, and their sensitivity to HI conditions increases excitotoxic damage (2)

( i ) V/[E] (min 1 ) values from (d-f) were extrapolated (mean SEM)

The normal process of aging is associated with a decrease in glutathione activity, which can result in increased oxidative activity

By inducing autophagy, resveratrol promotes the degradation of damaged cellular components, leading to cell death and inhibition of tumor growth

N Engl J Med 367: 817825, 2012

Remaining challenges include particle aggregation and potential toxicity, which have limited the number of polymer-based nanomedicines approved for clinical use [21]
