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doi: 10.3389/fendo.2012.00131 107 YangSYGoldspinkG
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Shallower depths (0.25-0.5mm) enhance product absorption with minimal trauma
The study found that NNMT inhibitors "reduced intracellular 1-MNA, increased intracellular NAD+ and S-(5-adenosyl)-L-methionine (SAM), and suppressed lipogenesis." This metabolic improvement occurs within days of starting treatment, before any weight loss becomes measurable
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