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IL-13 switches on the CCL26 gene to synthesize eotaxin-3, which is overexpressed in vivo in the esophageal transcriptome of EoE (Blanchard et al ., 2007)
2014;61:A4807
Pathological increases in local concentrations of ROS cause oxidative stress (102)
Recently, 6-hydroxymelatonin was seen to inhibit cytochrome C release from the mitochondria, suppress caspase 3 activity, and stabilize the mitochondrial membrane potential, thereby protecting against the neuronal cell death induced by oxygenglucoseserum deprivation in cultured cells [26,27,28,29]
