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Future research should build on this framework by prioritizing well-powered, longitudinal, and mechanistically integrated study designs that combine precise cycle phase verification with multi-omics approaches (e.g., metabolomics, transcriptomics, and microbiome profiling)

Chronic suppression of food intake could lead to muscle loss, potentially resulting in sarcopenia [40]

Despite increased regulatory issues around special populations, including people who are pregnant or lactating in clinical trials, additional studies in pregnant populations are planned

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