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In each of these disorders, therapeutic elevation of MnSOD levelsthrough genetic overexpression, pharmacologic mimetics, or upstream regulators like SIRT3 or Nrf2consistently reduces the ROS burden and limits neuronal injury [199,201,205,212,216]

doi: 10.26599/FSHW.2022.9250035 48 GialamaD.VadukulD

Introduction There is an increasing concern about the ecological effect of the use of pesticides

Alfayez M, Kantarjian HM, Short NJ, Assi R, Khouri M, Ravandi F, Paul S, Rausch CR, Nasnas P, Borthakur G , DiNardo CD, Kadia TM, Daver NG, Garcia-Manero G, Naqvi K, Bose P, O'Brien SM, Cortes JE, Jabbour EJ

Through clinical experience and extensive molecular investigation of tumors, clinically significant subgroups of glioblastoma with similar genetic expression and methylation profiles have been identified [96, 97]
