is inducing glutathione pro-oxidant response and accelerated ferroptosis caused by synergetic Au(I) release in hypercarbon-centered gold(I) cluster prodrugs Glutathione Depletion and Stalwart Anticancer
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It is also, at the blend level, a hypothesis

Water soluble or hydrophilic antioxidants are active in the blood plasma while the water insoluble antioxidants protect the cell membranes

Han H.-H

The other, in whom only 5% is available to cells, is not

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