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The liver is then burdened with these incoming toxins and must attempt to process them before they reach systemic circulation

In contrast, it would appear that the neurologic effects of cobalamin deficiency are due to metabolic disturbances unrelated to purine synthesis because the neurologic deficits may develop independently of the hematologic abnormalities, and folate supplementation will not prevent or reverse these deficits

Sivaprasad, R., Nagaraj, M., & Varalakshmi, P

Its relevance in skin biology isnt synthetic its innate

Red blood cell generation, cell metabolism, neuron function, and DNA synthesis are all aided by it

Apr 15 2006;173(8):897-901
