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Furthermore, using a murine cholangitis model, the researchers clarified the underlying mechanisms: butyrate activates peroxisome proliferator-activated receptor delta (PPARD) to promote fatty acid -oxidation (FAO)-mediated metabolic reprogramming

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While it's known for its powerful fat-releasing (lipolytic) effects, it also influences muscle growth, blood sugar levels, and cellular growth (the IGF-1 pathway)