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The molecular mechanism of this response involves phosphorylation of the translational initiator eukaryotic initiation factor 2-) at Ser51 residues

Also, vitamin B12 deficiency tends to come on very slowly, so people often go through a long period of being mildly deficient

Variant expression is quantified by local assembly and allele-specific quantification of mutated and reference transcripts

All patients received an NAC loading dose of 150 mg/kg over one hour, followed by 50 mg/kg for 4 h, and then a continuous infusion of 100 mg/kg over the next 16 h

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This leaves a substantial population seeking alternatives to surgery