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Watch for Signs of Copper Toxicity While GHK-Cu is generally well tolerated, overexposure to copper (especially in individuals with impaired detox pathways) can cause symptoms such as: Nausea or gastrointestinal upset Headaches Mood swings or irritability Metallic taste in the mouth If any of these symptoms occur, discontinue use and contact your healthcare provider

[DOI] [PMC free article] [PubMed] [Google Scholar] 225.Ahluwalia GS, Grem JL, Hao Z, Cooney DA

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213,214 This would trigger the subsequent mtDNA-cGAS-STING pathway, activating the downstream inflammatory response

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