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Most subjects experienced no change in constipation, with one subject reporting improvement, and four reporting a slight worsening

During and after dosing, no abnormalities were noted in the laboratory or clinical evaluations, and the patients reported no potentially drug- related adverse effects

doi: 10.1104/pp.118.2.471

Therefore, lipid peroxides are considered to be the proximal executors of ferroptosis (8)

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